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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10100078 B1

PDFFull Text
Date of Patent:
Oct. 16, 2018

Filed:

May. 25, 2017

Nanoparticles, process for preparation and use thereof as carrier for amphipatic and hydrophobic molecules in fields of medicine including cancer treatment and food related compounds

Applicant:

MX Adjuvac Ab, Enkoping, SE;

Inventors:

Bror Morein, Uppsala, SE;

Saideh Berenjian, Uppsala, SE;

Kafei Hu, Uppsala, SE;

Assignee:

MX Adjuvac AB, Enkoping, SE;

Attorney:

Andrus Intellectual Property Law, LLP

Primary Examiner:

Albert M Navarro

Int. Cl.
CPC ...
G01N 33/536 (2006.01); C07J 9/00 (2006.01); A61K 31/255 (2006.01); A61K 31/337 (2006.01); A61K 31/52 (2006.01); A61K 31/593 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 39/145 (2006.01); A61K 39/39 (2006.01); A61K 36/73 (2006.01); C12Q 1/48 (2006.01); G01N 33/50 (2006.01); A61K 9/51 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07J 9/00 (2013.01); A61K 9/5123 (2013.01); A61K 31/255 (2013.01); A61K 31/337 (2013.01); A61K 31/52 (2013.01); A61K 31/593 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 36/73 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/39 (2013.01); C12Q 1/485 (2013.01); G01N 33/5011 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55577 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16234 (2013.01); G01N 2800/52 (2013.01); Y10T 428/2982 (2015.01);
Abstract

The present invention regards nanoparticles comprising a sterol and a component derived fromMolina selected from quillaja acid andsaponin, which nanoparticles do not comprise a phospholipid. It also relates to a composition comprising the nanoparticles, and the use thereof as adjuvant, especially in vaccines, as carriers for amphipathic or hydrophobic molecules and as agents for treatment of cancer. Further, it regards a method for producing the phospholipid-free nano particles, a method for the treatment of cancer and a method for assessing the applicability of the cancer treating method.

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