The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Oct. 20, 2014
Applicants:

Suzhou Vigonvita Life Sciences Co., Ltd., Jiangsu, CN;

Topharman Shanghai Co., Ltd., Shanghai, CN;

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Inventors:

Zheng Liu, Shanghai, CN;

Chunhui Wu, Shanghai, CN;

Yongjian Liu, Shanghai, CN;

Rongxia Zhang, Shanghai, CN;

Yang He, Shanghai, CN;

Guanghui Tian, Shanghai, CN;

Jingshan Shen, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/70 (2006.01); C07D 409/12 (2006.01); C07D 333/54 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); C07D 333/54 (2013.01); C07D 333/70 (2013.01);
Abstract

The present invention relates to the methods for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, specifically, the present invention relates to a new method for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, and the key intermediates, and salts thereof provided during the preparation. The preparation method has a mild reaction condition, stable intermediate, easy operation, and uses cheap and easy-to-get reagents, thus it saves the synthesis cost, shortens the production cycle, improves the yield and product quality, and is suitable for mass production.


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