The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Nov. 06, 2014
Kissei Pharmaceutical Co., Ltd., Matsumoto-shi, Nagano, JP;
Kazuo Shimizu, Azumino, JP;
Takashi Miyagi, Azumino, JP;
Kohsuke Ohno, Azumino, JP;
Yasunori Ueno, Azumino, JP;
Yusuke Onda, Azumino, JP;
Hikaru Suzuki, Azumino, JP;
KISSEI PHARMACEUTICAL CO., LTD., Matsumoto-shi, Nagano, JP;
Abstract
The present invention provides a new compound which has NKreceptor antagonist activity, whose CYP3A4 inhibitory activity is reduced compared to aprepitant, and which are useful for the prevention or treatment of cancer-chemotherapy-induced nausea and vomiting. That is, the present invention relates to carboxymethyl piperidine derivatives represented by the following formula (I) or a pharmaceutically acceptable salt thereof. Wherein, ring A is a benzene ring or the like; ring B is a pyridine ring or the like; Ris Calkyl or Calkoxy; Rand Rare a hydrogen atom or methyl; and n is an integral number from 0 to 5.