The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Aug. 23, 2017
Applicant:
Scinopharm Taiwan, Ltd., Tainan, TW;
Inventors:
Tsung-Yu Hsiao, Kaohisiung, TW;
Yung-Hung Chang, Taichung, TW;
Assignee:
SCINOPHARM TAIWAN, LTD., Tainan, TW;
Primary Examiner:
Int. Cl.
CPC ...
C07D 237/32 (2006.01);
U.S. Cl.
CPC ...
C07D 237/32 (2013.01);
Abstract
Provided herein are novel processes and methods for making 4-[(3-[(4-cyclopropylcarbonyl)piperazin-1-yl]carbonyl)-4-fluorophenyl]methyl(2H)phthalazin-1-one (Olaparib) and intermediates thereof. Olaparib is a poly ADP ribose polymerase (PARP) inhibitor useful in the treatment of cancers. Benefits of the present disclosure include the use of less toxic compounds and improved yields.