The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Sep. 22, 2015
Applicants:

Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;

Snu R&db Foundation, Seoul, KR;

Inventors:

Tae Sun Park, Seoul, KR;

Lak Shin Jeong, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/32 (2006.01); A61K 31/4453 (2006.01); C07C 225/16 (2006.01);
U.S. Cl.
CPC ...
C07D 211/32 (2013.01); A61K 31/4453 (2013.01); C07C 225/16 (2013.01); A61K 2300/00 (2013.01);
Abstract

The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for prevention or treatment of metabolic diseases, and a functional food composition using the same for improvement or relief of metabolic diseases. The pentadienoyl piperidine derivative of the present invention inhibits the differentiation of preadipocytes, reduces body weight, visceral fat, blood lipid levels, and blood glucose levels, improves a blood liver function index, and suppresses metabolic inflammation responses. Thus, ultimately, the derivative can be usefully used as a medicine or a functional food composition, which exhibits the preventive or therapeutic activity for metabolic diseases selected from the group consisting of obesity, diabetes, dyslipidemia, fatty liver and insulin resistance syndrome.


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