The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Jan. 31, 2014
Applicant:

Chromacon Ag, Zurich, CH;

Inventors:

Thomas Müller-Späth, Zurich, CH;

Lars Aumann, Zurich, CH;

Guido Strohlein, Zurich, CH;

Michael Bavand, Lenzburg, CH;

Nicole Ulmer, Schlieren, CH;

Assignee:

ChromaCon AG, Zurich, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/02 (2006.01); G01N 30/26 (2006.01); G01N 30/34 (2006.01); B01D 15/18 (2006.01); B01D 15/38 (2006.01); G01N 30/46 (2006.01); G01N 30/44 (2006.01); G01N 30/38 (2006.01);
U.S. Cl.
CPC ...
B01D 15/1871 (2013.01); B01D 15/1807 (2013.01); B01D 15/1864 (2013.01); B01D 15/3804 (2013.01); B01D 15/3809 (2013.01); G01N 30/02 (2013.01); G01N 30/26 (2013.01); G01N 30/34 (2013.01); G01N 30/38 (2013.01); G01N 30/44 (2013.01); G01N 30/46 (2013.01); G01N 30/461 (2013.01); G01N 30/462 (2013.01); G01N 30/463 (2013.01); G01N 30/468 (2013.01);
Abstract

A chromatographic purification method for the isolation of a desired product fraction from a mixture using 2 chromatographic columns, comprises, within one cycle to be carried out at least once, the following steps: a first batch step, wherein said columns are disconnected and a first column is loaded with feed and its outlet is directed to waste, and from a second column desired product is recovered and subsequently the second column is regenerated; a first interconnected step, wherein the outlet of the first column is connected to the inlet of the second column, the first column is loaded beyond its dynamic breakthrough capacity with feed, and the outlet of the second column is directed to waste, a second batch step analogous to the first batch step but with exchanged columns; and a second interconnected step, analogous to the first interconnected step but with exchanged columns.


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