The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Oct. 11, 2011
Applicants:

Ari Ilkka Mikael Partanen, Bethesda, MD (US);

Matthew Robert Dreher, Rockville, MD (US);

Pavel Sergeyevich Yarmolenko, Silver Spring, MD (US);

Antti Johannes Viitala, Espoo, FI;

Julia Kristina Enholm, Helsingfors, FI;

Max Oskar Kohler, Espoo, FI;

Inventors:

Ari Ilkka Mikael Partanen, Bethesda, MD (US);

Matthew Robert Dreher, Rockville, MD (US);

Pavel Sergeyevich Yarmolenko, Silver Spring, MD (US);

Antti Johannes Viitala, Espoo, FI;

Julia Kristina Enholm, Helsingfors, FI;

Max Oskar Kohler, Espoo, FI;

Assignees:

Profound Medical Inc., Mississauga, CA (US);

National Institutes of Health, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 7/00 (2006.01); A61N 7/02 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01); A61N 5/10 (2006.01); G01R 33/48 (2006.01); G01R 33/50 (2006.01); A61B 90/00 (2016.01);
U.S. Cl.
CPC ...
A61N 7/00 (2013.01); A61N 7/02 (2013.01); G01R 33/4814 (2013.01); A61B 2017/00084 (2013.01); A61B 2018/00642 (2013.01); A61B 2018/00666 (2013.01); A61B 2018/00678 (2013.01); A61B 2018/00791 (2013.01); A61B 2090/374 (2016.02); A61N 5/10 (2013.01); A61N 2005/1085 (2013.01); A61N 2005/1087 (2013.01); G01R 33/4804 (2013.01); G01R 33/50 (2013.01);
Abstract

A therapeutic apparatus () comprising a high intensity focused ultrasound system () for heating a target zone (). The therapeutic apparatus further comprises a magnetic resonance imaging system (). The therapeutic apparatus further comprises a memory () containing machine executable instructions () for execution by a processor (). Execution of the instructions cause the processor to: generate () heating commands () which cause the high intensity focused ultrasound system to sonicate the subject; repeatedly acquire () magnetic resonance data () during execution of the heating commands; repeatedly calculate () a spatially dependent parameter (); and repeatedly modify () the heating commands in accordance with the spatially dependent parameter such that within the target zone the spatially dependent parameter remains below a first predetermined threshold and above a second predetermined threshold.


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