The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Sep. 10, 2015
Applicant:

Vlp Therapeutics, Llc, Wilmington, DE (US);

Inventors:

Wataru Akahata, Kensington, MD (US);

Ryuji Ueno, Easton, MD (US);

Assignee:

VLP Therapeutics, LLC, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/53 (2013.01); A61K 2039/575 (2013.01); C12N 2770/24023 (2013.01); C12N 2770/24123 (2013.01); C12N 2770/24134 (2013.01); Y02A 50/386 (2018.01); Y02A 50/388 (2018.01); Y02A 50/39 (2018.01); Y02A 50/394 (2018.01); Y02A 50/396 (2018.01);
Abstract

Provided is a virus like particle comprising one or more flavivirus structural proteins, and a composition or vaccine comprising thereof, its use in the prevention or treatment of flavivirus infection. The flavivirus structural protein contains at least one amino acid alteration in the envelope region. Examples of flavivirus contains dengue virus.


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