The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
May. 03, 2013
Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, Heidelberg, DE;
Ruprecht-karls-universitaet Heidelberg, Heidelberg, DE;
Zahari Raykov, Heidelberg, DE;
Jean Rommelaere, Heidelberg, DE;
Nathalia Giese, Schriesheim, DE;
Marc Aprahamian, Heidelberg, DE;
Deutsches Krebsforschungszentrum Stiftung des oeffentlichen Rechts, Heidelberg, DE;
Ruprecht-Karls-Universiaet Heidelberg, Heidelberg, DE;
Abstract
A parvovirus characterized by a CpG-enriched genome, wherein the genome contains at least 2 additional CpG inserts that are not present in the wild type genome is described as well as the use of said parvovirus, e.g., a parvovirus based on parvovirus H1, LuIII, Mouse minute virus (MMV), Mouse parvovirus (MPV), Rat minute virus (RMV), Rat parvovirus (RPV), Rat virus (RV), vectors based on the foregoing viral species, and/or cells capable of actively producing the foregoing viral species for the preparation of a pharmaceutical composition, e.g., for the treatment of cancer, preferably pancreas carcinoma, hepatoma or lymphoma.