The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Jun. 20, 2017
Applicant:
Zhejiang Dtrm Biopharma Co. Ltd., Shanghai, CN;
Inventor:
Wei He, Audubon, PA (US);
Assignee:
ZHEJIANG DTRM BIOPHARMA CO. LTD., Hangzhou, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/436 (2006.01); A61K 31/437 (2006.01); A61K 31/4162 (2006.01); A61K 31/635 (2006.01); A61K 45/06 (2006.01); C07D 487/04 (2006.01); A61K 31/454 (2006.01);
U.S. Cl.
CPC ...
A61K 31/635 (2013.01); A61K 31/436 (2013.01); A61K 31/454 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01); A61K 31/4162 (2013.01); A61K 2300/00 (2013.01);
Abstract
Described herein are combination therapies for cancer (such as lymphoid malignancies) and immune diseases (such as autoimmune diseases and inflammatory diseases). The therapies comprise the combined use of inhibitors of BTK, mTOR kinase, and Bcl-2 or their signaling pathways, and immunomodulatory drugs. Also described are pharmaceutical compositions and kits comprising these inhibitors.