The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Jul. 29, 2015
Therapeuticsmd, Inc., Boca Raton, FL (US);
Julia Amadio, Boca Raton, FL (US);
Annette Shadiack, Somerset, NJ (US);
Peter H. R. Persicaner, Boca Raton, FL (US);
Richard Winneker, Penllyn, PA (US);
Jason Legassie, Stuart, FL (US);
Thorsteinn Thorsteinsson, Boynton Beach, FL (US);
Ajay Ghanta, North Palm Beach, FL (US);
TherapeuticsMD, Inc., Boca Raton, FL (US);
Abstract
This disclosure relates to transdermal pharmaceutical compositions containing progesterone in combination with one or more solubilizing agents and penetration enhancers, wherein the pharmaceutical compositions are formulated as creams for topical administration. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, and d-limonene. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, a penetration enhancer (e.g., propylene glycol, a fatty acid ester of propylene glycol, a glycol ether), and optionally d-limonene. In certain embodiments, the pharmaceutical compositions further include estradiol. Methods for treating conditions associated with hormone deficiency in a subject are also described.