The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Nov. 09, 2016
Shandong Luye Pharmaceutical Co., Ltd., Yantai, Shandong Province, CN;
Nanjing Luye Pharmaceutical Co., Ltd, Nanjing, Jiangsu Province, CN;
Kaoxiang Sun, Yantai, CN;
Rongcai Liang, Yantai, CN;
Qilin Wang, Yantai, CN;
Wenyan Wang, Yantai, CN;
Wanhui Liu, Yantai, CN;
Youxin Li, Yantai, CN;
Shandong Luye Pharmaceutical Co., Ltd., Yantai, CN;
Nanjing Luye Pharmaceutical Co., Ltd., Nanjing, CN;
Abstract
A risperidone sustained release microsphere formulation is provided. The microsphere formulation includes risperidone or 9-hydroxy risperidone or salts thereof, and a polymer blend having a first uncapped lactide-glycolide copolymer and a second uncapped lactide-glycolide copolymer, in which the first uncapped lactide-glycolide copolymer is a copolymer with a high intrinsic viscosity and the second uncapped lactide-glycolide copolymer is a copolymer with a low intrinsic viscosity. The sustained release micro sphere formulation according to an embodiment of the present disclosure is suitable for large-scale industrialized production with improved stability, the in vivo release behavior of which will not change after long-term storage.