The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2018

Filed:

Feb. 16, 2016
Applicant:

Nektar Therapeutics, San Francisco, CA (US);

Inventors:

Antoni Kozlowski, Huntsville, AL (US);

Timothy A. Riley, Worcester, MA (US);

Samuel P. McManus, Guntersville, AL (US);

Assignee:

Nektar Therapeutics, San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/337 (2006.01); A61K 47/60 (2017.01); C07D 305/14 (2006.01); C08G 65/329 (2006.01); C08G 65/333 (2006.01);
U.S. Cl.
CPC ...
A61K 31/337 (2013.01); A61K 47/60 (2017.08); C07D 305/14 (2013.01); C08G 65/329 (2013.01); C08G 65/33337 (2013.01); C08L 2203/02 (2013.01);
Abstract

Among other aspects, provided herein are multi-arm polymeric prodrug conjugates of taxane-based compounds and/or fluorinated forms thereof. Methods of preparing such conjugates as well as methods of administering the conjugates are also provided. Upon administration to a patient, release of the taxane-based compound is achieved.


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