The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2018
Filed:
Feb. 03, 2012
William E. Grieshober, Jr., East Amherst, NY (US);
James S. Jones, Newton, MA (US);
Semyon Kogan, Newton, MA (US);
Ilya Ilyin, St. Petersburg, RU;
Natella I. Enukashvily, St. Petersburg, RU;
Yana A. Filkina, St. Petersburg, RU;
Alexander N. Shumeev, St. Petersburg, RU;
Stanislav Kolchanov, St. Petersburg, RU;
William E. Grieshober, Jr., East Amherst, NY (US);
James S. Jones, Newton, MA (US);
Semyon Kogan, Newton, MA (US);
Ilya Ilyin, St. Petersburg, RU;
Natella I. Enukashvily, St. Petersburg, RU;
Yana A. Filkina, St. Petersburg, RU;
Alexander N. Shumeev, St. Petersburg, RU;
Stanislav Kolchanov, St. Petersburg, RU;
Rich Technologies Holding Company, LLC, Buffalo, NY (US);
Abstract
Provided is a method for reducing apoptosis in nucleated cells. The method entails holding nucleated cells in a container and adding a gas containing xenon to the container so that the pressure inside the container reaches between 0.5 to 4.0 Atm above ambient pressure; holding the container at between 0.5 to 4.0 Atm above ambient pressure for a period of time during which the temperature in the container is between 22° C. and 37° C.; lowering the temperature in the container to between 0.1° C. and 10° C. while maintaining the pressure of 0.5 to 4.0 Atm above ambient pressure and holding the container for a period of time; and reducing the pressure in the container to ambient pressure and increasing the temperature to 22° C.-37° C. By performing these steps, the cells undergo less apoptosis than a reference.