The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2018

Filed:

Jan. 23, 2015
Applicant:

Atlas Genetics Limited, Bristol, GB;

Inventors:

Helen Braven, Melksham, GB;

Russell Keay, Melksham, GB;

Assignee:

Atlas Genetics Limited, Trowbridge, Wiltshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); C12Q 1/6816 (2018.01); C12Q 1/6823 (2018.01); C12Q 1/686 (2018.01); G01N 27/30 (2006.01); G01N 27/416 (2006.01); G01N 33/487 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
G01N 27/3277 (2013.01); B01L 7/52 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6823 (2013.01); G01N 27/308 (2013.01); G01N 27/416 (2013.01); G01N 33/48721 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/18 (2013.01); G01N 2458/30 (2013.01);
Abstract

The invention provides a method of probing for a nucleic acid comprising: contacting a nucleic acid solution with an oligonucleotide probe labelled with an electrochemically active marker, providing conditions at which the probe is able to at least partially hybridize with any complementary target sequence which may be present in the nucleic acid solution, selectively degrading either hybridized, partially hybridized or unhybridized nucleic acid probe, and electrochemically determining information relating to the electrochemically active marker. The invention further provides novel molecules with use in methods of the invention.


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