The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2018

Filed:

Nov. 12, 2013
Applicants:

Biontech Ag, Mainz, DE;

Ganymed Pharmaceuticals Ag, Mainz, DE;

Tron—translationale Onkologie an Der Universitatsmedizin Der Johannes Gutenberg-universitat Mainz Gemeinnutzige Gmbh, Mainz, DE;

Inventors:

Ugur Sahin, Mainz, DE;

Ozlem Tureci, Mainz, DE;

Christiane Stadler, Bensheim, DE;

Julia Holland, Mainz, DE;

Hayat Bahr-Mahmud, Wiesbaden, DE;

Tim Beissert, Gross-Gerau, DE;

Laura Plum, Mainz, DE;

Fabrice Le Gall, Mainz, DE;

Arne Jendretzki, Mainz-Kostheim, DE;

Markus Fiedler, Halle an der Saale, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); C07K 16/28 (2013.01); C07K 16/30 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/74 (2013.01);
Abstract

The present invention provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.


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