The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2018
Filed:
Dec. 11, 2015
Applicant:
Abbvie Inc., North Chicago, IL (US);
Inventors:
Lorenzo Benatuil, Northborough, MA (US);
Kangwen Deng, Shrewsbury, MA (US);
Denise Karaoglu Hanzatian, Natick, MA (US);
Maria A. Argiriadi, Southborough, MA (US);
Assignee:
AbbVie Inc., North Chicago, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/46 (2006.01); G01N 33/53 (2006.01); C07K 14/705 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); G01N 33/566 (2006.01); A61K 38/00 (2006.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 38/00 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 47/6849 (2017.08); C07K 14/705 (2013.01); C07K 16/468 (2013.01); G01N 33/53 (2013.01); G01N 33/566 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/705 (2013.01);
Abstract
The disclosure provides binding proteins that specifically bind to LRP-8 and optionally cross the blood brain barrier (BBB), localize to the brain and/or localize to the spinal cord.