The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2018
Filed:
Sep. 12, 2012
Applicants:
Bruce M. Spiegelman, Waban, MA (US);
Pontus Bostrom, Boston, MA (US);
Inventors:
Bruce M. Spiegelman, Waban, MA (US);
Pontus Bostrom, Boston, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/78 (2006.01); C07K 19/00 (2006.01); C07K 14/435 (2006.01); C07K 16/18 (2006.01); C07K 14/575 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07K 14/435 (2013.01); C07K 14/575 (2013.01); C07K 14/78 (2013.01); C07K 16/18 (2013.01); C07K 19/00 (2013.01);
Abstract
The invention provides compositions and methods for brown fat induction and activity through modulation of Fndc5 activity and/or expression. Also provided are methods for preventing or treating metabolic disorders in a subject through modulation of Fndc5 activity and/or expression. Further provided are methods for identifying compounds that are capable of modulating Fndc5 activity and/or expression.