The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2018

Filed:

Jan. 11, 2017
Applicant:

Gilead Connecticut, Inc., Foster City, CA (US);

Inventors:

Peter A. Blomgren, Issaquah, WA (US);

Kevin S. Currie, North Bend, WA (US);

Jeffrey E. Kropf, Issaquah, WA (US);

Seung H. Lee, Sammamish, WA (US);

Scott A. Mitchell, Kenmore, WA (US);

Douglas G. Stafford, Niskayuna, NY (US);

Jianjun Xu, Seattle, WA (US);

Assignee:

Gilead Connecticut, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01); C07D 471/04 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 9/0053 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); G01N 2333/9121 (2013.01);
Abstract

Certain imidazopyrazines of Formula I and pharmaceutical compositions thereof are provided herein: Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.


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