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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10093668 B1

PDFFull Text
Date of Patent:
Oct. 09, 2018

Filed:

Oct. 28, 2016

Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (mnk1) and 2 (mnk2)

Applicant:

Northwestern University, Evanson, IL (US);

Inventors:

Gary E. Schiltz, Naperville, IL (US);

Rama K. Mishra, Chicago, IL (US);

Leonidas C. Platanias, Glencoe, IL (US);

Javier Izquierdo-Ferrer, Chicago, IL (US);

Assignee:

Northwestern University, Evanston, IL (US);

Attorney:

Andrus Intellectual Property Law, LLP

Primary Examiner:

Deepak R Rao

Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 471/04 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01);
Abstract

Disclosed are substituted aromatic N-heterocyclic compounds. The disclosed compounds typically exhibit kinase inhibition activity, for example, and inhibit Mnk1 kinase and/or Mnk2 kinase. The disclosed compounds may be used in pharmaceutical compositions and methods for treating diseases or disorders associated with Mnk1 kinase activity and/or Mnk2 kinase activity, such as cancers, diabetes, autism, and fragile X syndrome.

Find Patent Forward Citations

Schiltz, Gary. (2018). Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (mnk1) and 2 (mnk2) (U.S. Patent No. 10093668). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10093668

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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