The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2018
Filed:
Mar. 09, 2017
Hoffmann-la Roche Inc., Nutley, NJ (US);
Chugai Pharmaceutical Inc., Kita-Ku, Tokyo, JP;
Francisco Javier Lopez-Tapia, Honolulu, HI (US);
Sung-Sau So, Verona, NJ (US);
Qi Qiao, San Diego, CA (US);
Romyr Dominique, Ridgewood, NJ (US);
HOFFMANN-LA ROCHE INC., Nutley, NJ (US);
CHUGAI PHARMACEUTICAL CO., Tokyo, JP;
Abstract
This application discloses compounds according to generic Formula (I): wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are useful for the treatment of oncological, auto-immune, and inflammatory diseases caused by aberrant B-cell activation. Also disclosed are compositions containing compounds of Formula (I) and at least one carrier, diluent or excipient.