The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2018

Filed:

Aug. 16, 2016
Applicants:

Uwm Research Foundation, Inc., Milwaukee, WI (US);

Women and Infants Hospital of Rhode Island, Providence, RI (US);

Inventors:

Alexander E. Arnold, Milwaukee, WI (US);

Preetpal Singh Sidhu, Milwaukee, WI (US);

Premchendar Nandhikonda, Milwaukee, WI (US);

Rakesh K. Singh, Barrington, RI (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 45/06 (2006.01); A61K 31/404 (2006.01); C07D 407/12 (2006.01); C07D 209/16 (2006.01); C07D 209/10 (2006.01); C07D 209/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/404 (2013.01); A61K 45/06 (2013.01); C07D 209/10 (2013.01); C07D 209/14 (2013.01); C07D 209/16 (2013.01); C07D 407/12 (2013.01);
Abstract

Described herein are compounds, pharmaceutical compositions and methods for inhibiting the expression of a vitamin D receptor target gene, inhibiting interactions between the vitamin D receptor and at least one vitamin D receptor coactivator, for treating cancer in a subject, and for inhibiting angiogenesis in a subject.


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