IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10093624 B1

PDFFull Text
Date of Patent:
Oct. 09, 2018

Filed:

Oct. 12, 2015

Nampt and rock inhibitors

Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Rick F. Clark, Gurnee, IL (US);

Michael L. Curtain, Pleasant Prairie, WI (US);

Todd M. Hansen, Grayslake, IL (US);

Howard R. Heyman, Deerfield, IL (US);

Helmut Mack, Ludwigshafen, DE;

Michael Michaelides, Libertyville, IL (US);

Marina A. Pliushchev, Vernon Hills, IL (US);

Omar J. Shah, Issaquah, WA (US);

Bryan K. Sorensen, Antioch, IL (US);

Ramzi Sweis, Lake Bluff, IL (US);

Chris Tse, Libertyville, IL (US);

Anil Vasudevan, Union Grove, WI (US);

Kevin R. Woller, Antioch, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorney:

Glen Gesicki

Primary Examiner:

Jeffrey H Murray

Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/44 (2006.01); C07D 209/44 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01); C07D 407/14 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); A61K 31/437 (2006.01); A61K 31/496 (2006.01); A61K 31/4985 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 209/44 (2013.01); A61K 31/437 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01); C07D 407/14 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of treating diseases during which ROCK is expressed.

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