The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2018
Filed:
Mar. 21, 2013
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Timo Heinrich, Gross-Umstadt, DE;
Frank Zenke, Darmstadt, DE;
Mireille Krier, Darmstadt, DE;
Manja Friese-Hamim, Moerfelden-Walldorf, DE;
Jeyaprakashnarayanan Seenisamy, Bangalore, IN;
Assignee:
MERCK PATENT GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/402 (2006.01); A61K 31/4035 (2006.01); A61K 31/4184 (2006.01); A61K 31/445 (2006.01); A61K 31/45 (2006.01); A61K 31/451 (2006.01); A61K 31/541 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); C07D 207/12 (2006.01); C07D 207/16 (2006.01); C07D 207/24 (2006.01); C07D 207/26 (2006.01); C07D 207/267 (2006.01); C07D 207/277 (2006.01); C07D 211/60 (2006.01); C07D 211/74 (2006.01); C07D 211/76 (2006.01); C07D 211/78 (2006.01); C07D 223/08 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 417/06 (2006.01); C07D 223/10 (2006.01);
U.S. Cl.
CPC ...
C07D 207/277 (2013.01); A61K 31/40 (2013.01); A61K 31/402 (2013.01); A61K 31/4035 (2013.01); A61K 31/4184 (2013.01); A61K 31/445 (2013.01); A61K 31/45 (2013.01); A61K 31/451 (2013.01); A61K 31/541 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 207/12 (2013.01); C07D 207/16 (2013.01); C07D 207/24 (2013.01); C07D 207/26 (2013.01); C07D 207/267 (2013.01); C07D 211/60 (2013.01); C07D 211/74 (2013.01); C07D 211/76 (2013.01); C07D 211/78 (2013.01); C07D 223/08 (2013.01); C07D 223/10 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 417/06 (2013.01); Y02A 50/411 (2018.01);
Abstract
Described are cyclic amide compounds of the formula (I): in which R, R, R, R, R, R, X and Y have the meanings as described. The compounds are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumors.