The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2018
Filed:
Sep. 04, 2017
Applicant:
Emory University, Atlanta, GA (US);
Inventors:
Huw M. L. Davies, Duluth, GA (US);
Spandan Chennamadhavuni, Natick, MA (US);
Andrei Bakin, Buffalo, NY (US);
Assignee:
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/216 (2006.01); A61K 31/194 (2006.01); C07C 69/73 (2006.01); C07C 259/06 (2006.01); C07C 69/736 (2006.01); C07C 67/31 (2006.01); C07C 57/42 (2006.01); C07C 51/00 (2006.01); A61K 31/405 (2006.01); A61K 31/36 (2006.01); A61K 31/357 (2006.01); A61K 31/343 (2006.01); C07D 307/80 (2006.01); C07D 209/24 (2006.01); C07C 201/12 (2006.01); C07C 69/604 (2006.01); C07C 69/618 (2006.01); C07C 69/65 (2006.01); C07C 69/732 (2006.01); C07C 69/734 (2006.01); C07C 69/738 (2006.01); C07D 317/60 (2006.01); C07D 319/18 (2006.01); C07D 209/26 (2006.01); C07D 209/34 (2006.01); C07D 307/79 (2006.01); C07C 205/56 (2006.01); C07D 317/68 (2006.01);
U.S. Cl.
CPC ...
C07C 69/73 (2013.01); A61K 31/194 (2013.01); A61K 31/216 (2013.01); A61K 31/343 (2013.01); A61K 31/357 (2013.01); A61K 31/36 (2013.01); A61K 31/405 (2013.01); C07C 51/00 (2013.01); C07C 57/42 (2013.01); C07C 67/31 (2013.01); C07C 69/604 (2013.01); C07C 69/618 (2013.01); C07C 69/65 (2013.01); C07C 69/732 (2013.01); C07C 69/734 (2013.01); C07C 69/736 (2013.01); C07C 69/738 (2013.01); C07C 201/12 (2013.01); C07C 205/56 (2013.01); C07C 259/06 (2013.01); C07D 209/24 (2013.01); C07D 209/26 (2013.01); C07D 209/34 (2013.01); C07D 307/79 (2013.01); C07D 307/80 (2013.01); C07D 317/60 (2013.01); C07D 317/68 (2013.01); C07D 319/18 (2013.01);
Abstract
The disclosure relates to TAK1 inhibitors, compositions, and uses related thereto. In certain embodiments, the disclosure relates to compounds of formula I, pharmaceutical compositions having a compound of formula I, and methods of treating or preventing cancer by administering an effective amount of a pharmaceutical composition having a compound of formula I to a subject in need thereof.