The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2018
Filed:
Mar. 14, 2013
Biothera, Inc., Eagan, MN (US);
William J. Grossman, Third Lake, IL (US);
Mary A. Antonysamy, Woodbury, MN (US);
Richard M. Walsh, Lino Lakes, MN (US);
Mariana I. Nelson, Rosemount, MN (US);
Nandita Bose, Plymouth, MN (US);
Michael E. Danielson, St. Paul, MN (US);
Kyle S. Michel, Eagan, MN (US);
Biothera, Inc., Eagan, MN (US);
Abstract
This disclosure describes, in one aspect, a composition that includes a β-glucan component and an antibody component that specifically binds to the β-glucan. In another aspect, this disclosure describes a method of increasing a subject's response to β-glucan immunotherapy. Generally, the method includes identifying the subject as a low binder of β-glucan and administering to the subject a composition that comprises a β-glucan moiety conjugated to the therapeutic antibody. In some cases, the therapeutic antibody can be an anti-tumor antibody.