The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2018

Filed:

Mar. 24, 2017
Applicant:

Ab Science, Paris, FR;

Inventors:

Alain Moussy, Paris, FR;

Jean-Pierre Kinet, Lexington, MA (US);

Colin Mansfield, Ecully, FR;

Assignee:

AB SCIENCE, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/428 (2006.01); A61K 9/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 9/0053 (2013.01); A61K 31/428 (2013.01); A61P 25/00 (2018.01);
Abstract

Disclosed is a method for treating patients afflicted with non-aggressive or moderately aggressive amyotrophic lateral sclerosis (ALS) whose rate of change of the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) prior to treatment initiation is <1.1 points per month, the method including administering a tyrosine kinase inhibitor or mast cell inhibitor, in particular masitinib, or a pharmaceutically acceptable salt or solvate thereof, optionally in combination with at least one pharmaceutically active ingredient.


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