The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2018
Filed:
Apr. 18, 2016
Applicant:
Taiho Pharmaceutical Co., Ltd., Chiyoda-ku, JP;
Inventors:
Tetsuya Sugimoto, Tsukuba, JP;
Hidekazu Takahashi, Tsukuba, JP;
Morihiro Mitsuya, Tsukuba, JP;
Norio Masuko, Tsukuba, JP;
Hiroshi Sootome, Tsukuba, JP;
Assignee:
TAIHO PHARMACEUTICAL CO., LTD., Chiyoda-ku, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); A61K 31/337 (2006.01); C07D 417/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A61K 31/337 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract
A novel compound which has an excellent aurora A-selective inhibitory action and is useful as an orally administrable anticancer agent is provided. Also, a novel agent for potentiation of anti-tumor effect of microtubule agonists, which include a taxane anticancer agent, and a combination therapy are provided. A piperidine compound represented by a general formula (I) or a salt thereof: