The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Feb. 06, 2009
Applicants:
Christian Korfhage, Hilden, DE;
Dirk Loeffert, Hilden, DE;
Ralf Peist, Hilden, DE;
Nicolas Rudinger, Duesseldorf, DE;
Inventors:
Christian Korfhage, Hilden, DE;
Dirk Loeffert, Hilden, DE;
Ralf Peist, Hilden, DE;
Nicolas Rudinger, Duesseldorf, DE;
Assignee:
QIAGEN GMBH, Hilden, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6844 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6844 (2013.01); C12Q 1/6844 (2013.01); C12Q 2523/125 (2013.01); C12Q 2527/137 (2013.01); C12Q 2531/119 (2013.01);
Abstract
The present invention relates to a reaction mixture for the amplification of nucleic acids, the non-methylated cytosine bases of which have been converted to uracil bases by means of a bisulfition reaction. The invention also discloses methods for amplifying bisulfited nucleic acid and for determining the nucleic acid methylation state, and also kits based on the reaction mixture according to the invention.