The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Jan. 06, 2015
Applicant:
Nanyang Technological University, Singapore, SG;
Inventors:
Nguan Soon Tan, Singapore, SG;
Han Chung Chong, Singapore, SG;
Ming Jie Tan, Singapore, SG;
Royston Huang, Singapore, SG;
Assignee:
Nanyang Technologies University, Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); C07K 16/22 (2013.01); C12N 15/1138 (2013.01); A61K 2039/505 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2330/50 (2013.01);
Abstract
The invention provides an antibody specific to the ANGPTL4 protein capable of neutralizing proliferation and methods of making and using the same. The antibody of the invention is further directed to the C terminal region of the protein and may be capable of neutralizing cell proliferation and treating cancer. The antibody may be monoclonal and/or humanized antibody.