The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Nov. 23, 2016
Applicant:

Integrated Dna Technologies, Inc., Coralville, IA (US);

Inventors:

Mark Aaron Behlke, Coralville, IA (US);

Richard Owczarzy, Coralville, IA (US);

Yong You, Iowa City, IA (US);

Joseph Alan Walder, Chicago, IL (US);

Kim Lennox, North Liberty, IA (US);

Assignee:

Integrated DNA Technologies, Inc., Coralville, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/35 (2006.01); G01N 33/58 (2006.01); C12N 15/113 (2010.01); C12N 15/11 (2006.01); C12Q 1/6876 (2018.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/111 (2013.01); C12Q 1/6876 (2013.01); C12N 2310/11 (2013.01); C12N 2310/141 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/344 (2013.01); C12N 2310/352 (2013.01); C12N 2310/3529 (2013.01); C12N 2320/51 (2013.01);
Abstract

The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.


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