The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Dec. 11, 2015
Applicant:

The Methodist Hospital, Houston, TX (US);

Inventors:

Haifa Shen, Houston, TX (US);

Mauro Ferrari, Houston, TX (US);

Jianliang Shen, Houston, TX (US);

Mingzhen Zhang, Houston, TX (US);

Assignee:

The Methodist Hospital, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/713 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 31/7088 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/5031 (2013.01); A61K 9/5146 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract

Disclosed are methods and compositions containing functionalized nanoporous silicon particles, useful in a variety of diagnostic and/or therapeutic regimens for delivery of genetic constructs to one or more cells, tissues, and/or organs of interest. Also provided are methods for introducing into selected host cells one or more selected nucleic acid molecules. The present disclosure is also directed to a method of treating a tumor, comprising the step of administering to an individual one or more of the compositions and formulations thereof as described herein.


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