The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Mar. 02, 2011
Applicants:
Blake Wiedenheft, Oakland, CA (US);
Kaihong Zhou, Moraga, CA (US);
Jennifer A. Doudna, Berkeley, CA (US);
Inventors:
Blake Wiedenheft, Oakland, CA (US);
Kaihong Zhou, Moraga, CA (US);
Jennifer A. Doudna, Berkeley, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C12N 9/22 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 38/465 (2013.01); C12P 19/34 (2013.01);
Abstract
Provided herein are methods of using a Cas1 polypeptide to generate nucleic fragments from a DNA substrate. These methods may be performed in vitro or in vivo. Also provided are methods of screening for modulators of Cas1.