The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Mar. 10, 2016
Applicant:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Robert G. Dennis, Chapel Hill, NC (US);

John A. van Aalst, Walton, KY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/00 (2006.01); C12M 3/00 (2006.01); C12N 5/0775 (2010.01); C12M 1/42 (2006.01); C12M 1/36 (2006.01); A61F 2/02 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); C12M 1/12 (2006.01); C12M 1/34 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12M 21/08 (2013.01); A61F 2/02 (2013.01); A61L 27/3691 (2013.01); A61L 27/3817 (2013.01); A61L 27/3821 (2013.01); A61L 27/3895 (2013.01); C12M 25/14 (2013.01); C12M 35/02 (2013.01); C12M 35/04 (2013.01); C12M 41/46 (2013.01); C12M 41/48 (2013.01); C12N 5/0654 (2013.01); C12N 5/0655 (2013.01); C12N 5/0665 (2013.01); A61L 2430/02 (2013.01); A61L 2430/06 (2013.01); C12N 2506/1369 (2013.01); C12N 2527/00 (2013.01);
Abstract

Methods, devices and systems are disclosed for vibration induced tissue engineering. Apparatuses, devices, systems and methods are provided for engineering a tissue from stem cells using vibratory signals. A tissue engineering apparatus, device, or system can include a transmitter configured to transmit a signal to a receiver, a receiver configured to receive a signal from a transmitter, a holding structure configured to hold one or more mesenchymal stem cells (MSC), and a vibratory actuator in communication with the receiver and configured to generate a vibratory signal that is applied to the MSC.


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