The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Dec. 04, 2015
Applicant:
AM Chemicals Llc, Oceanside, CA (US);
Inventors:
Andrei Pavel Guzaev, Escondido, CA (US);
Vladimir Y. Vvedenskiy, San Diego, CA (US);
Assignee:
AM CHEMICALS LLC, Oceanside, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 23/00 (2006.01); C07H 21/02 (2006.01); C07H 19/04 (2006.01); C07H 19/20 (2006.01); C07H 19/10 (2006.01); C07H 19/048 (2006.01); C07H 19/16 (2006.01); C07H 21/00 (2006.01); C07H 19/06 (2006.01);
U.S. Cl.
CPC ...
C07H 19/16 (2013.01); C07H 19/06 (2013.01); C07H 21/00 (2013.01); Y02P 20/55 (2015.11);
Abstract
Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.