The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Nov. 09, 2017
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

John Y. L. Chung, Edison, NJ (US);

Kevin Campos, Berkeley Heights, NJ (US);

Edward Cleator, Cambridge, GB;

Robert F. Dunn, Towaco, NJ (US);

Andrew Gibson, Hoddesdon, GB;

R. Scott Hoerrner, Westfield, NJ (US);

Stephen Keen, Hoddesdon, GB;

Dave Lieberman, Hoddesdon, GB;

Zhuqing Liu, Edison, NJ (US);

Joseph Lynch, Plainfield, NJ (US);

Kevin M. Maloney, Piscataway, NJ (US);

Feng Xu, Staten Island, NY (US);

Nobuyoshi Yasuda, Mountainside, NJ (US);

Naoki Yoshikawa, Hyogo, JP;

Yong-Li Zhong, Edison, NJ (US);

Assignee:

MERCK SHARP & DOHME CORP., Rahway, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 263/06 (2006.01); C07D 207/09 (2006.01); C07D 403/12 (2006.01); A61K 31/4196 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4196 (2013.01); A61K 31/519 (2013.01); C07D 207/09 (2013.01); C07D 263/06 (2013.01); C07D 403/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.


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