The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Aug. 07, 2017
Applicant:
Eisai R&d Management Co., Ltd., Bunkyo-ku, Tokyo, JP;
Inventors:
J. Eric Carlson, Merrimack, NH (US);
Lynn Hawkins, Concord, MA (US);
Sally Ishizaka, Weston, MA (US);
Shawn Schiller, Haverhill, MA (US);
Chikako Ogawa, Basel, CH;
Atsushi Endo, Andover, MA (US);
Assignee:
EISAI R&D MANAGEMENT CO., LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 413/04 (2006.01); C07D 215/48 (2006.01); C07D 471/04 (2006.01); C07D 487/10 (2006.01); C07D 471/10 (2006.01); C07D 401/14 (2006.01); C07D 401/10 (2006.01); C07D 403/14 (2006.01); C07D 451/04 (2006.01); C07D 487/04 (2006.01); C07D 493/10 (2006.01); C12Q 1/6897 (2018.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 215/48 (2013.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 451/04 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C07D 493/10 (2013.01); C12Q 1/6897 (2013.01); G01N 33/5023 (2013.01); G01N 33/5047 (2013.01); C07B 2200/07 (2013.01);
Abstract
Embodiments of the disclosure relate to selectively substituted quinoline compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.