The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Feb. 16, 2017
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Xiamen University, Xiamen, CN;
Xiao-kun Zhang, San Diego, CA (US);
Ying Su, San Diego, CA (US);
Hu Zhou, San Diego, CA (US);
Wen Liu, La Jolla, CA (US);
Pei-Qiang Huang, Xiamen, CN;
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, San Diego, CA (US);
XIAMEN UNIVERSITY, Xiamen, CN;
Abstract
Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a tumor microenviroment. For example, the methods and compositions described herein can be used to induce apoptosis in a cancer cell. Further, the compositions described herein, including Sulindac and analogs thereof, can be used to target this pathway for the treatment or prevention of cancer in human patients.