The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Feb. 23, 2016
Toray Fine Chhemicals Co., Ltd., Tokyo, JP;
Hisafumi Hiraga, Tokai, JP;
Takeshi Nishikawa, Tokai, JP;
Abstract
A method produces a 3-phenylisoserine derivative by protecting an amino group of a compound represented by General Formula (1) (wherein Rrepresents a phenyl group, or a phenyl group having a substituent; Rrepresents an alkali metal, alkaline earth metal, or nitrogen base; and Rrepresents a hydrogen atom, methyl group, benzyl group, p-methoxybenzyl group, tert-butyl group, methoxymethyl group, 2-tetrahydropyranyl group, ethoxyethyl group, acetyl group, pivaloyl group, benzoyl group, trimethylsilyl group, triethylsilyl group, or tert-butyldimethylsilyl group) in water or a mixed solvent containing water to obtain a particular compound; extracting with a Cether-based solvent; replacing at least part of the Cether-based solvent with a C-Caliphatic alcohol while removing the Cether-based solvent and water to perform esterification reaction; and isolating at 0 to 30° C. to obtain a 3-phenylisoserine derivative represented by General Formula (2).