The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2018
Filed:
Apr. 03, 2017
Combined therapy of alpha-1-antitrypsin and temporal t-cell depletion for preventing graft rejection
Applicant:
Ben Gurion University of the Negev Research and Development Authority, Beer Sheva, IL;
Inventor:
Eli Lewis, Beer Sheva, IL;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/57 (2006.01); A61K 39/395 (2006.01); A61K 35/39 (2015.01); A61K 38/14 (2006.01); A61K 38/19 (2006.01); A61K 38/21 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/395 (2013.01); A61K 35/39 (2013.01); A61K 38/14 (2013.01); A61K 38/191 (2013.01); A61K 38/217 (2013.01); A61K 38/57 (2013.01); A61K 39/3955 (2013.01); A61K 39/39541 (2013.01); C07K 16/40 (2013.01); A61K 2039/505 (2013.01);
Abstract
A method of preventing or treating xenotransplant rejection in a subject in need thereof is disclosed. The method comprises administering a therapeutically effective amount of alpha-1-antitrypsin (AAT) in combination with a therapeutically effective amount of an anti-CD8 antibody or an antigen binding fragment thereof.