The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Sep. 24, 2015
Applicants:

Shanghai Haiyan Pharmaceutical Technology Co., Ltd., Pudong New Area Shanghai, CN;

Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, Jiangsu, CN;

Inventors:

Yunzhou Jin, Pudong New Area Shanghai, CN;

Ping Bu, Pudong New Area Shanghai, CN;

Qi He, Pudong New Area Shanghai, CN;

Jiong Lan, Pudong New Area Shanghai, CN;

Fusheng Zhou, Pudong New Area Shanghai, CN;

Liang Zhang, Pudong New Area Shanghai, CN;

Xiangyu He, Pudong New Area Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4985 (2006.01); A61K 31/53 (2006.01); A61K 31/4188 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 31/4188 (2013.01); C07D 487/04 (2013.01);
Abstract

Azabicyclo derivatives, a preparation process, and medical use thereof are provided. In particular, azabicyclo derivatives of formula (I), pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs thereof are described. The azabicyclo derivatives of formula (I) are useful as Epidermal Growth Factor Receptor (EGFR) inhibitors. The definitions of the variable R groups in the azabicyclo derivatives of formula (I) are described in the specification.


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