The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Nov. 30, 2015
Applicant:

Ignyta, Inc., San Diego, CA (US);

Inventors:

Zachary Dolph Hornby, San Diego, CA (US);

Gang Li, San Diego, CA (US);

David Wesley Anderson, Poway, CA (US);

Garrett M. Brodeur, Wynnewood, PA (US);

Radhika Iyer, Wilmington, DE (US);

Assignee:

IGNYTA, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 403/12 (2006.01); C07D 231/56 (2006.01); C07D 405/12 (2006.01); A61K 31/4188 (2006.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/4188 (2013.01); A61K 31/4745 (2013.01); C07D 231/56 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01);
Abstract

Disclosed are methods of treating neuroblastoma in a cancer patient by administration of a Trk inhibitor in combination with one more chemotherapeutic agents. Also disclosed are pharmaceutical compositions comprising a Trk inhibitor and one or more chemotherapeutic agents.


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