The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Aug. 12, 2015
Applicant:

Strides Shasun Limited, Tamil Nadu, IN;

Inventors:

Jeffrey Stuart Bergman, Hertfordshire, GB;

Sampathkumar Devarajan, Chennai, IN;

Selvakumar Ramalingam, Tamil Nadu, IN;

Anandsenthil Vel Palanisamy, Tamil Nadu, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/06 (2006.01); A61K 31/192 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/38 (2006.01); A61K 47/10 (2017.01); A61K 47/18 (2017.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61K 9/06 (2013.01); A61K 9/0014 (2013.01); A61K 31/192 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/18 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61K 47/38 (2013.01);
Abstract

Stable non-alcoholic transdermal hydrogel of dexibuprofen was prepared by using a simple manufacturing process, and the experimental trials showed that the pH modifying agent, antioxidant and water miscible solvent are the essential excipients to obtain stable non-alcoholic transdermal hydrogel of dexibuprofen. The dexibuprofen hydrogel prepared using carbopol as a gelling polymer produced an opaque gel, whereas hydrogel prepared using hyroxypropyl methylcellulose (HPMC) as a gelling polymer produced a transparent gel. There was no significant changes observed with respect to physical description, pH, assay and particularly to the related substance values when the hydrogels were subjected to the stability study at accelerated condition (40° C./75% RH) for 3 months in laminated tubes.


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