The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2018

Filed:

Feb. 14, 2017
Applicant:

University of Pittsburgh - of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Xucai Chen, Pittsburgh, PA (US);

Francois T. H. Yu, Pittsburgh, PA (US);

Flordeliza S. Villanueva, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 8/08 (2006.01); A61B 8/12 (2006.01); A61B 8/00 (2006.01); A61M 5/00 (2006.01); A61K 49/22 (2006.01); G01S 7/52 (2006.01);
U.S. Cl.
CPC ...
A61B 8/481 (2013.01); A61B 8/0891 (2013.01); A61B 8/12 (2013.01); A61B 8/445 (2013.01); A61B 8/4488 (2013.01); A61B 8/4494 (2013.01); A61B 8/5207 (2013.01); A61B 8/5246 (2013.01); A61K 49/223 (2013.01); A61M 5/007 (2013.01); G01S 7/52022 (2013.01);
Abstract

A method of imaging a blood vessel includes delivering a bubble-based contrast agent within the vessel and positioning at least one ultrasound device in the vicinity of the bubble-based contrast agent within the vessel. A first burst of low-frequency ultrasound energy can be delivered to excite the bubble-based contrast agent into oscillation within the vessel, and a second burst of high-frequency ultrasound energy can be delivered at the excited bubble-based contrast agent. A return signal from the burst of high-frequency ultrasound energy can be received and processed to obtain one or more images.


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