The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2018
Filed:
Jul. 05, 2016
Applicant:
Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Jef De Brabander, Flower Mound, TX (US);
Jerry W. Shay, Dallas, TX (US);
Wentian Wang, Irving, TX (US);
Deepak Nijhawan, Dallas, TX (US);
Pano Theodoropoulos, Dallas, TX (US);
Assignee:
Board of Regents of the University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); A61K 31/4545 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/4725 (2006.01); A61K 31/635 (2006.01); A61K 31/5377 (2006.01); A61K 31/655 (2006.01); A61K 31/513 (2006.01); A61K 31/55 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 413/04 (2006.01); C07D 417/14 (2006.01); C07D 453/02 (2006.01); C07D 211/96 (2006.01); G01N 33/48 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/513 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 31/635 (2013.01); A61K 31/655 (2013.01); C07D 211/96 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 453/02 (2013.01); G01N 33/48 (2013.01); G01N 2333/99 (2013.01);
Abstract
The described invention provides methods for targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis.