The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2018
Filed:
Mar. 23, 2011
Dennis T. Brown, Raleigh, NC (US);
Raquel Hernandez, Raleigh, NC (US);
Malcolm E. Thomas, Raleigh, NC (US);
Katherine M. Smith, Raleigh, NC (US);
Dennis T. Brown, Raleigh, NC (US);
Raquel Hernandez, Raleigh, NC (US);
Malcolm E. Thomas, Raleigh, NC (US);
Katherine M. Smith, Raleigh, NC (US);
Research Development Foundation, Carson City, NV (US);
Arbovax, Inc., Raleigh, NC (US);
Abstract
Methods and compositions concerning mutant flaviviruses with host range mutations. In some embodiments the invention concerns nucleotide sequences that encode mutant flavivirus proteins. Viruses comprising these sequences that display reduced replication in mammalian cells are provided. In further aspects of the invention, flavivirus vaccine compositions are provided. In another embodiment the invention provides methods for vaccination against flavivirus infection.