The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2018
Filed:
Jun. 19, 2017
Applicants:
Daniel E. Levy, San Mateo, CA (US);
Patricio Abarzúa, West Caldwell, NJ (US);
Inventors:
Daniel E. Levy, San Mateo, CA (US);
Patricio Abarzúa, West Caldwell, NJ (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/24 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 473/34 (2006.01);
U.S. Cl.
CPC ...
C07D 473/34 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention relates to novel adenine based inhibitors of adenylyl cyclase of the formula: wherein X, L, R1, R2, R5 are those defined herein. Compounds of the present invention are useful to treat cardiovascular diseases. The present invention also relates to a method of preventing heart failure by administering an effective amount of compound according to the invention following vascular injury and reperfusion therapy.