The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2018
Filed:
Aug. 20, 2009
Robert I. Tepper, Weston, MA (US);
Russell Hirsch, Los Altos Hills, CA (US);
Jason E. Fuller, Boston, MA (US);
Jessica L. Duda, Boston, MA (US);
Craig Muir, Davis, CA (US);
Jeffrey S. Ross, Lebanon Springs, NY (US);
J. Christopher Flaherty, Topsfield, MA (US);
Robert I. Tepper, Weston, MA (US);
Russell Hirsch, Los Altos Hills, CA (US);
Jason E. Fuller, Boston, MA (US);
Jessica L. Duda, Boston, MA (US);
Craig Muir, Davis, CA (US);
Jeffrey S. Ross, Lebanon Springs, NY (US);
J. Christopher Flaherty, Topsfield, MA (US);
Kibur Medical, Inc., Boston, MA (US);
Abstract
Described here are devices, systems, and kits for delivering substances to tissues. The devices generally include one or more chambers () and a reservoir () within each chamber. The reservoir may locally deliver a microdose amount of a substance to a target tissue. In some variations, a microdose amount is used in early human studies, e.g., before a phase I clinical trial, to evaluate the effect of the substance on a target tissue, or to obtain pharmacokinetic or metabolic data. In other variations, a microdose amount is used to locally treat a medical condition. In yet other variations, a microdose amount is used to locally deliver a contrast agent for a structural or functional imaging procedure. Methods for delivering and retrieving the devices from the target tissue are also described.