The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2018
Filed:
Apr. 18, 2017
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Ruoxi Lan, Waltham, MA (US);
Bayard R. Huck, Sudbury, MA (US);
Xiaoling Chen, Chestnut Hill, MA (US);
Lizbeth C. Deselm, Melrose, MA (US);
Hui Qiu, Acton, MA (US);
Yufang Xiao, Lexington, MA (US);
Constantin Neagu, Belmont, MA (US);
Igor Mochalkin, Westford, MA (US);
Theresa L. Johnson, Salem, MA (US);
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 239/48 (2006.01); C07D 413/04 (2006.01); C07D 417/14 (2006.01); C07D 405/12 (2006.01); C07D 417/12 (2006.01); C07D 239/49 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); C07D 239/48 (2013.01); C07D 239/49 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract
The invention provides novel heterocyclic amine compounds according to Formula (I) and their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.