The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2018

Filed:

Jul. 21, 2014
Applicants:

National University of Singapore, Singapore, SG;

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Cho Hong James Goh, Singapore, SG;

Kok Hiong Thomas Teh, Singapore, SG;

Pujiang Shi, Singapore, SG;

Hoi Po James Hui, Singapore, SG;

Jun Li, Singapore, SG;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/08 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/46 (2006.01); A61L 27/48 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61F 2/08 (2013.01); A61L 27/3604 (2013.01); A61L 27/3834 (2013.01); A61L 27/46 (2013.01); A61L 27/48 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61F 2002/087 (2013.01); A61F 2210/0076 (2013.01); A61F 2240/001 (2013.01); A61L 2300/414 (2013.01);
Abstract

The present invention relates to a device for the interfacial augmentation of tissue grafts for the purpose of tendon and ligament reconstruction. The inventive device works both as a delivery vessel for osteoconductive and osteoinductive factors and as a scaffold to stimulate and support bone ingrowth and comprises a tubular composite silk sheath, said tubular composite silk sheath comprising: a backbone consisting of a tubular silk mesh, and a carrier material consisting of a porous silk sponge, wherein said tubular silk mesh consists of degummed silk fibroin fibers, wherein said porous silk sponge comprises silk fibroin fibers and hydroxyapatite particles and said tubular silk mesh and said porous silk sponge form a composite material. The present invention is also directed to a method for the manufacturing of such augmentation devices, a method for fixation of the thus fabricated tissue interface augmentation devices onto ligament or tendon grafts, a method for applying such devices for ligament and/or tendon reconstruction to tendon grafts, as well as their application in ligament and tendon reconstruction.


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